Ack! Istaria won't run! Now what?

Istaria on Windows Vista

Launching Under Vista - Note: Istaria is now Vista compatible.  This information is deprecated.

Istaria on Windows

Website Launcher - Note: Istaria now uses a standalond launcher.  This information is deprecated.

Bypassing the Launcher - Starting Horizons without using a launcher.

Istaria (Horizons) on Linux (wine)

http://appdb.winehq.org/appview.php?iVersionId=2696|Horizons on Linux - Horizons (kind of) runs under the latest wine builds!